Skip to Main Content (Press Enter)
×
Home
Persone
Pubblicazioni
Strutture
Competenze
IT
EN
☰
UNI-FIND
|
UNI-FIND
cnr.it
IT
EN
×
Home
Persone
Pubblicazioni
Strutture
Competenze
☰
Pubblicazioni
BIOORGANIC & MEDICINAL CHEMISTRY
Rivista
Codice:
E022400
ISSN:
0968-0896
Dati Generali
Dati Generali
Pubblicazioni (138)
Pulisci
Ordina Pubblicazioni:
ascendente
decrescente
1,3-Dialkyl-8-(hetero)aryl-9-OH-9-deazaxanthines as potent A2B adenosine receptor antagonists: Design, synthesis, structure affinity and structure selectivity relationships
Articolo
11C-Radiosynthesis and preliminary human evaluation of the disposition of the ACE inhibitor [11C]zofenoprilat
Articolo
3-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-6-substituted-3,6-diazabicyclo[3.1.1]hep
Articolo
5-(Trifluoromethyl)-beta-l-2'-deoxyuridine, the L-enantiomer of trifluorothymidine: stereospecific synthesis and antiherpetic evaluations.
Articolo
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family.
Articolo
A SPR strategy for high-throughput ligand screenings based on synthetic peptides mimicking a selected subdomain of the target protein: A proof of concept on HER2 receptor
Articolo
A SPR strategy for high-throughput ligand screenings based on synthetic peptides mimicking a selected subdomain of the target protein: A proof of concept on HER2 receptor
Articolo
A new and efficient synthesis of substituted 6-(2-dialkylamono)ethyl pyrimidine and 4-N, N-dialkyl-6-vinyl-cytosine derivatives and evaluation of their anti-rubella activity.
Articolo
A novel library of saccharin and acesulfame derivatives as potent and selective inhibitors of carbonic anhydrase IX and XII isoforms
Articolo
A possible prebiotic synthesis of purine, adenine, cytosine, and 4(3H)-pyrimidinone from formamide: Implications for the origin of life
Articolo
An ?-carbonic anhydrase from the thermophilic bacterium Sulphurihydrogenibium azorense is the fastest enzyme known for the CO(2) hydration reaction
Articolo
An o-nitrobenzyl scaffold for peptide ligation: synthesis and applications
Articolo
Anion inhibition profiles of alpha-, beta- and gamma-carbonic anhydrases from the pathogenic bacterium Vibrio cholerae
Articolo
Anion inhibition profiles of the complete domain of the eta-carbonic anhydrase from Plasmodium falciparum
Articolo
Anion inhibition profiles of the gamma-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei responsible of melioidosis and highly drug resistant to common antibiotics
Articolo
Anion inhibition studies of the alpha-carbonic anhydrase from the protozoan pathogen Trypanosoma cruzi, the causative agent of Chagas disease
Articolo
Anion inhibition study of the beta-carbonic anhydrase (CahB1) from the cyanobacterium Coleofasciculus chthonoplastes (ex-Microcoleus chthonoplastes)
Articolo
Antimalarial and antiproliferative evaluation of bis-steroidal tetraoxanes
Articolo
Antimalarial and antiproliferative evaluation of bis-steroidal tetraoxanes.
Articolo
Antimicrobial and Anti-Lipase Activity of Quercetin and Its C2-C16 3-O-Acyl-Esters
Articolo
Astersedifolioside A-C, three new oleane-type saponins with antiproliferative activity
Articolo
Benzenesulfonamide bearing imidazothiadiazole and thiazolotriazole scaffolds as potent tumor associated human carbonic anhydrase IX and XII inhibitors
Articolo
Binding ability of a thymine-functionalized oligolysine towards nucleic acids
Articolo
Binding of triazole-linked galactosyl arylsulfonamides to galectin-3 affects Trypanosoma cruzi cell invasion
Articolo
Biocatalysed synthesis of b-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties
Articolo
Cloning, characterization and anion inhibition studies of a gamma-carbonic anhydrase from the Antarctic bacterium Colwellia psychrerythraea
Articolo
Cloning, characterization and anion inhibition study of a beta-class carbonic anhydrase from the caries producing pathogen Streptococcus mutans
Articolo
Cloning, characterization and anion inhibition study of the delta-class carbonic anhydrase (TweCA) from the marine diatom Thalassiosira weissflogii
Articolo
Comparison of the anion inhibition profiles of the beta- and gamma-carbonic anhydrases from the pathogenic bacterium Burkholderia pseudomallei
Articolo
Corrigendum to "Inhibition of human topoisomerase I and II and anti-proliferative effects on MCF-7 cells by new titanocene complexes" [Bioorg. Med. Chem. 23 (2015) 7302-7312]
Articolo
Corrigendum to "Silybins are stereospecific regulators of the 20S proteasome" [Bioorgan. Med. Chem. 66 (2022) 116813] (Bioorganic & Medicinal Chemistry (2022) 66, (S096808962200205X), (10.1016/j.bmc.2022.116813))
Articolo
Design, modelling, synthesis and biological evaluation of peptidomimetic phosphinates as inhibitors of matrix metalloproteinases MMP-2 and MMP-8.
Articolo
Design, synthesis and in vitro evaluation of new naphthylnitrobutadienes with potential antiproliferative activity: towards a structure/activity correlation.
Articolo
Design, synthesis, and structure-activity relationships of 1,3-dihydrobenzimidazol-2-one analogues as anti-HIV agents.
Articolo
Design, synthesis, binding and molecular modeling studies of new potent ligands of cannabinoid receptors
Articolo
Designed calix[8]arene-based ligand for selective tryptase surface recognition
Articolo
Determining the occurrence of a 3(10)-helix and an alpha-helix in two different segments of a lipopeptaibol antibiotic using TOAC, a nitroxide spin-labeled C-alpha-tetrasubstituted alpha-aminoacid
Articolo
Development of sulfonamides incorporating phenylacrylamido functionalities as carbonic anhydrase isoforms I, II, IX and XII inhibitors
Articolo
Dimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part II: Structural and biological characterization.
Articolo
Discovery of 4-sulfamoyl-phenyl-?-lactams as a new class of potent carbonic anhydrase isoforms I, II, IV and VII inhibitors: The first example of subnanomolar CA IV inhibitors
Articolo
Dithiocarbamates effectively inhibit the beta-carbonic anhydrase from the dandruff-producing fungus Malassezia globosa
Articolo
Dual Src and Abl inhibitors target wild type Abl and the AblT315I Imatinib-resistant mutant with different mechanisms.
Articolo
Effect of C-Ring Modifications in Benzo[c]quinolizin-3-ones, New Selective Inhibitors of Human 5?-Reductase 1
Articolo
Efficient and highly stereoselective synthesis of a betalactam inhibitor of the serine protease prostate-specific antigen
Articolo
Exploring the interest of 1, 2-dithiolane ring system in peptide chemistry. Synthesis of a chemotactic tripeptide and x-ray crystal structure of a 4-amino-1, 2-dithiolane-4-carboxylic acid derivative
Articolo
Fluorescent molecular rotors as sensors for the detection of thymidine phosphorylase
Articolo
Fmoc-protected iminosugar modified asparagine derivatives as building blocks for glycomimetics-containing peptides
Articolo
High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones.
Articolo
Homo- and heterodimeric Smac mimetics/IAP inhibitors as in vivo-active pro-apoptotic agents. Part I: Synthesis
Articolo
Identification of the stereochemical requirements in the 4-aryl-2-cycloalkylidenhydrazinylthiazole scaffold for the design of selective human monoamine oxidase B inhibitors
Articolo
Improved synthesis of daunomycin conjugates with triplex-forming oligonucleotides. The polypurine tract of HIV-1 as a target.
Articolo
Induction and Memory of Chirality in Porphyrin Hetero-Aggregates: the Role of the Central Metal Ion.
Articolo
Inhibition of Malassezia globosa carbonic anhydrase with phenols
Articolo
Inhibition of carbonic anhydrases from the extremophilic bacteria Sulfurihydrogenibium yellostonense (SspCA) and S. azorense (SazCA) with a new series of sulfonamides incorporating aroylhydrazone-, [1,2,4]triazolo[3,4-b][1,3,4]thiadiazinyl- or 2-(cyanophenylmethylene)-1,3,4-thiadiazol-3(2H)-yl moieties
Articolo
Inhibition of human topoisomerase I and II and anti-proliferative effects on MCF-7 cells by new titanocene complexes
Articolo
Inhibition of tumor-associated human carbonic anhydrase isozymes IX and XII by a new class of substituted-phenylacetamido aromatic sulfonamides
Articolo
Inhibition studies of bacterial, fungal and protozoan ?-class carbonic anhydrases with Schiff bases incorporating sulfonamide moieties
Articolo
Inhibitory effect of beta-diketones and their metal complexes on TNF-alpha induced expression of ICAM-1 on human endothelial cells
Articolo
Insights into MAPK p38a DFG flip mechanism by accelerated molecular dynamics
Articolo
Iodine-mediated cyclization of cannabigerol (CBG) expands the cannabinoid biological and chemical space
Articolo
Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1,6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors
Articolo
Kinetic properties and affinities for sulfonamide inhibitors of an alpha-carbonic anhydrase (CruCA4) involved in coral biomineralization in the Mediterranean red coral Corallium rubrum
Articolo
Malondialdehyde scavenging and aldose-derived Schiff bases transglycation properties of synthetic histidyl-hydrazide carnosine analogs
Articolo
Modulation of the activity of histone acetyltransferases by long chain alkylidenemalonates (LoCAMs)
Articolo
Molecular modeling study for the binding of zonisamide and topiramate to the human mitochondrial carbonic anhydrase isoform VA
Articolo
Natural and semisynthetic azaphilones as a new scaffold for Hsp90 inhibitors
Articolo
New antiviral drugs for the treatment of the common cold
Articolo
Non-peptide NK(1) receptor ligands based on the 4-phenylpyridine moiety.
Articolo
Novel 1,3-dihydro-benzimidazol-2-ones and their analogues as potent non-nucleoside HIV-1 reverse transcriptase inhibitors.
Articolo
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors.
Articolo
Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity
Articolo
Novel bioactive metabolites of dipyrone (metamizol)
Articolo
Novel diazabicycloalkane delta opioid agonists
Articolo
Novel sterically hindered cannabinoid CB1 receptor ligands.
Articolo
Novel sulfenamides and sulfonamides based on pyridazinone and pyridazine scaffolds as CB1 receptor ligand antagonists
Articolo
Novel thienocycloalkylpyridazinones as useful scaffolds for acetylcholinesterase inhibition and serotonin 5-HT6 receptor interaction
Articolo
Novel tricyclic Delta(2)-isoxazoline and 3-oxo-2-methyl-isoxazolidine derivatives: synthesis and binding affinity at neuronal nicotinic acetylcholine receptor subtypes.
Articolo
Paviosides A-H, eight new oleane type saponins from Aesculus pavia with cytotoxic activity
Articolo
Phthalazine PDE IV inhibitors: Conformational study of some 6-methoxy-1,4-disubstituted derivatives
Articolo
Physicochemical and biological study of selected hydrophobic polyethylenimine-based polycationic liposomes and their complexes with DNA.
Articolo
Poly(amidoamine) dendrimers show carbonic anhydrase inhibitory activity against ?-, ?-, ?- and ?-class enzymes
Articolo
Proline-Glutamate Chimeras in Isopeptides., Synthesis and Biological Evaluation of Conformationally Restricted Glutathione Analogues
Articolo
Protonography, a powerful tool for analyzing the activity and the oligomeric state of the gamma-carbonic anhydrase identified in the genome of Porphyromonas gingivalis
Articolo
Pyridobenzothiazole derivatives as new chemotype targeting the HCV NS5B polymerase.
Articolo
Quinazoline-sulfonamides with potent inhibitory activity against the alpha-carbonic anhydrase from Vibrio cholerae
Articolo
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy
Articolo
Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy
Articolo
Reassessing the melatonin pharmacophore--enantiomeric resolution, pharmacological activity, structure analysis, and molecular modeling of a constrained chiral melatonin analogue
Articolo
Recombinant thermoactive phosphoenolpyruvate carboxylase (PEPC) from Thermosynechococcus elongatus and its coupling with mesophilic/thermophilic bacterial carbonic anhydrases (CAs) for the conversion of CO2 to oxaloacetate
Articolo
Research on L-nucleosides. Synthesis and biological evaluation of a series of L- and D-2',3'-dideoxy-3'-[tris(methylthio)methyl]-beta-pentofuranosyl nucleosides.
Articolo
Role of the amino sugar in the DNA binding of disaccharide anthracyclines: crystal structure of the complex MAR70/d(CGATCG).
Articolo
Selective interactions of perylene derivatives having different side chainswith inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition.
Articolo
Selectivity of 3-bromo-isoxazoline inhibitors between human and Plasmodium falciparum glyceraldehyde-3-phosphate dehydrogenases
Articolo
Silybins are stereospecific regulators of the 20S proteasome
Articolo
Specific interactions with intra- and intermolecular G-quadruplex DNA structures by hydrosoluble coronene derivatives: A new class of telomerase inhibitors
Articolo
Stereocontrolled Synthesis and Biological Activity of two Diastereoisomers of the Potent HIV-1 Protease Inhibitor Saquinavir
Articolo
Stereocontrolled synthesis and biological activity of two diastereoisomers of the potent HIV-1 protease inhibitor saquinavir
Articolo
Structural insights into the interaction of a monoclonal antibody and Nodal peptides by STD-NMR spectroscopy
Articolo
Structure-affinity relationship studies on arylpiperazine derivatives related to quizapine as serotonin transporter ligands. Molecular basis of the selectivity SERT/5HT3 receptor
Articolo
Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist
Articolo
Sulfonamide inhibition profiles of the beta-carbonic anhydrase from the pathogenic bacterium Francisella tularensis responsible of the febrile illness tularemia
Articolo
Sulfonamide inhibition studies of the beta-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae
Articolo
Sulfonamide inhibition studies of the eta-class carbonic anhydrase from the malaria pathogen Plasmodium falciparum
Articolo
Sulfonamide inhibition studies of the gamma-carbonic anhydrase from the Antarctic cyanobacterium Nostoc commune
Articolo
Sulfonamide inhibition studies of two beta-carbonic anhydrases from the bacterial pathogen Legionella pneumophila
Articolo
Sulfonamide inhibition study of the carbonic anhydrases from the bacterial pathogen Porphyromonas gingivalis: the beta-class (PgiCAb) versus the gamma-class (PgiCA) enzymes.
Articolo
Synthesis and activity of fibrillogenesis peptide inhibitors related tothe 17-21 b-amyloid sequence
Articolo
Synthesis and activity studies of analogues of the rat selective toxicant norbormide
Articolo
Synthesis and biological evaluation of 1,8-naphthyridin-4(1H)-on-3-carboxamide derivatives as new ligands of cannabinoid receptors.
Articolo
Synthesis and biological evaluation of cyclic and branched peptide analogues as ligands for cholecystokinin type 1 receptor
Articolo
Synthesis and hyperpolarisation of eNOS substrates for quantification of NO production by H-1 NMR spectroscopy
Articolo
Synthesis of 4-(thiazol-2-ylamino)-benzenesulfonamides with carbonic anhydrase I, II and IX inhibitory activity and cytotoxic effects against breast cancer cell lines
Articolo
Synthesis of Bicyclic Molecular Scaffolds (BTAa). An Investigation Towards New Selective MMP-12 Inhibitors
Articolo
Synthesis of DEHP metabolites as biomarkers for GC MS evaluation of phthalates as endocrine disrupters
Articolo
Synthesis of all-trans anandamide: A substrate for fatty acid amide hydrolase with dual effects on rabbit platelet activation
Articolo
Synthesis of isoxazole-containing sulfonamides with potent carbonic anhydrase II and VII inhibitory properties
Articolo
Synthesis of novel diazatricyclodecanes (DTDs). Effects of structural variation at the C3' allyl end and at the phenyl ring of the cinnamyl chain on mu-receptor affinity and opioid antinociception
Articolo
Synthesis, biological evaluation and molecular investigation of fluorinated peroxisome proliferator-activated receptors alpha/gamma dual agonists
Articolo
Synthesis, biophysical characterization and anti-HIV activity of d(TG(3)AG) Quadruplexes bearing hydrophobic tails at the 5 '-end
Articolo
Synthesis, cannabinoid receptor affinity, molecular modeling studies and in vivo pharmacological evaluation of new substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides. 2. Effect of the 3-carboxamide substituent on the affinity and selectivity
Articolo
Synthesis, labeling, and biological evaluation of halogenated 2 quinolinecarboxamides as potential radioligands for the visualization of peripheral benzodiazepine receptors
Articolo
Synthesis, molecular modelling studies and biological evaluation of new oxoeoicosanoid receptor 1 agonists
Articolo
Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity
Articolo
TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach
Articolo
Targeting integrins: insights into structure and activity of cyclic RGD pentapeptide mimics containing azabicycloalkane amino acids
Articolo
Taste-guided identification of high potency TRPA1 agonists from Perilla frutescens
Articolo
Tetraiodobenzimidazoles are potent inhibitors of protein kinase CK2
Articolo
The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamide analogs with phenyl rings in the polar head group region
Articolo
The anandamide membrane transporter. Structure-activity relationships of anandamide and oleoylethanolamine analogs with phenyl rings in the polar head group region
Articolo
The extremo-?-carbonic anhydrase from the thermophilic bacterium Sulfurihydrogenibium azorense is highly inhibited by sulfonamides.
Articolo
The human tyrosine kinase Kit and its gatekeeper mutant T670I, show different kinetic properties: Implications for drug design
Articolo
The number and distances of positive charges of polyamine side chains in a series of perylene diimides significantly influence their ability to induce G-quadruplex structures and inhibit human telomerase
Articolo
The polypeptide 3(10)-helix as a template for molecular recognition studies. Structural characterization of a side-chain functionalized octapeptide
Articolo
The proteoglycan region of the tumor-associated carbonic anhydrase isoform IX acts as anintrinsic buffer optimizing CO2 hydration at acidic pH values characteristic of solid tumors
Articolo
Trans fatty acids and radical stress: what are the real culprits?
Articolo
Tricyclic pyrazoles. Part 2: Synthesis and biological evaluation of novel 4,5-dihydro-1H-benzo[g]indazole-based ligands for cannabinoid receptors.
Articolo
alfa-Peptide/beta-sulfonamidopeptide hybrids: Analogs of the chemotactic agent for-Met-Leu-Phe-OMe
Articolo
alpha-Peptide/beta-sulfonamidopeptide hybrids: Analogs of the chemotactic agent for-Met-Leu-Phe-OMe
Articolo
No Results Found
«
‹
{pageNumber}
›
»
{startItem} - {endItem} di {itemsNumber}
5 per pagina
10 per pagina
30 per pagina
vedi tutti
