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BLOOD

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Codice:

E023052

ISSN:

0006-4971

Dati Generali

Dati Generali

Pubblicazioni (163)

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"A prospective study of residual- desease monitoring of ALL1/AF4 transcript in patients with t(4;11) acute lymphoblastic leukemia

Articolo

"in vivo " activation of the human delta globin gene promoter

Contributo in Atti di convegno

(alpha)alpha5.3: A novel alpha+thalassemia deletion with the breakpoints in the alpha2-globin gene and in close proximity to an Alu family repeat between the pseudoalpha2- and pseudoalpha1-globin genes.

Articolo

A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site.

Articolo

A New FLVCR Isoform Able to Support Erythropoiesis.

Abstract

A T-cell epitope encoded by a subset of HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation.

Articolo

A novel MLL/AF4 fusion gene lacking the AF4 transactivating domain in infant acute lymphoblastic leukemia.

Articolo

A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through alpha5beta1 integrin

Articolo

A spontaneous mutation produced a novel elongated ?-globin chain structural variant (Hb Agnana) with a thalassemia-like phenotype

Articolo

A spontaneous mutation produced a novel elongated ß globin chain structural variant (Hb Agnana) with a thalassemia like phenotype

Articolo

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

Articolo

ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.

Articolo

Acquired copy-neutral loss of heterozygosity of chromosome 1p as a molecular event associated with marrow fibrosis in MPL-mutated myeloproliferative neoplasms

Articolo

Activated human NK and CD8+ T cells express both TNF-related apoptosis-inducing ligand (TRAIL) and TRAIL receptors but are resistant to TRAIL-mediated cytotoxicity,

Articolo

Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID

Articolo

Alternative, out-of-frame runt/MTG8 transcripts are encoded by the derivative(8) chromosome in the t(8;21) of acute myeloid leukemia M2

Articolo

Amelioration of Sardinian beta-0 thalassemia by genetic modifiers

Articolo

Anti-CD3? mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: Therapeutic implications

Articolo

Anti-CD3e mAb improves thymic architecture and prevents autoimmune manifestations in a mouse model of Omenn syndrome: therapeutic implications

Articolo

Atypical features of familial hemophagocytic lymphohistiocytosis

Articolo

Autocrine NGF is essential for cell survival and viral maturation in HHV-8 infected primary effusion lymphoma cells.

Articolo

Autologous HSCT for severe progressive multiple sclerosis in a multicenter trial: impact on disease activity and quality of life.

Articolo

Band 3 is an anchor protein and a target for SHP-2 tyrosine phosphatase in human erythrocytes.

Articolo

Beta-min Globin gene expression is preferentially reduced in EKLF KO mice.

Articolo

Blood Glutathione Detects Prooxidant Patterns in Patients with Mild Hyperhomocysteinemia at Risk for Atherothrombotic Vascular Events.

Articolo

Bone marrow CD8 cells down-modulate membrane IL-7R{alpha} expression and exhibit increased STAT-5 and p38 MAPK phosphorylation in the organ environment.

Articolo

Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets

Articolo

Brief report MicroRNAs modulate the angiogenic properties of HUVECs

Articolo

CD44 cross-linking on peripheral blood t lymphocytes induces th1 cytokines production

Abstract

CD44 ligation on peripheral blood polymorphonuclear cells induces interleukin- 6 production.

Articolo

CD44 ligation on peripheral blood polymorphonuclear cells induces interleukin-6 production

Articolo

CD49d promotes disease progression in chronic lymphocytic leukemia: new insights from CD49d bimodal expression

Articolo

CD59 Deficiency Is Critical for C3 Binding on Red Blood Cells of Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH) during Anti-C5 Treatment (eculizumab)

Abstract

CLINICAL AND MOLECULAR ANALYSIS OF HAEMOGLOBIN H DISEASE IN SARDINIA: HAEMATOLOGICAL, OBSTETRIC AND CARDIAC ASPECTS IN PATIENTS WITH DIFFERENT GENOTYPES.

Articolo

Characterization and Prognostic Relevance of Circulating Microvesicles in Chronic Lymphocytic Leukemia

Articolo

Chromatin accessibility, p300, and histone acetylation define PML-RAR? and AML1-ETO binding sites in acute myeloid leukemia.

Articolo

Clinical relevance of clonal hematopoiesis in persons aged >=80 years

Articolo

Combined Famd and ANOVA Investigation Leads to Significant Association Between the hOCT1/ABCB1 Diplotype and Both Efficacy and Tolerability in Patients Affected By Chronic Myeloid Leukemia

Contributo in Atti di convegno

Combined treatment with temozolomide and poly(ADP-ribose) polymerase inhibitor enhances survival of mice bearing hematologic malignancy at the central nervous system site.

Articolo

Comparison in the rhesus monkey model of in vivo gene marking with amphotrophic and VSV-G pseudotyped retroviral vectors.

Poster

Complement Activation in Paroxysmal Nocturnal Hemoglobinuria (PNH) Causes Oxidative Damage Which May Affect Response to Eculizumab

Abstract

Complement-mediated oxidative damage of red cells impairs response to eculizumab in a G6PD-deficient patient with PNH

Articolo

DELINEATION OF THE MOLECULAR BASIS OF DELTA AND NORMAL HBA-2 BETA-THALASSEMIA

Articolo

DELTA-PLUS THALASSEMIA IN SARDINIA ITALY

Articolo

Delayed Embryonic to Adult Globin Switching in HMGB2 Knock Out Mice

Abstract

Delayed Embryonic to Adult Globin Switching in HMGB2 Knock Out Mice

Contributo in Atti di convegno

Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies

Articolo

Different Hemoglobin switching pattern of beta-thalassemia mutations at the proximal and distal human beta globin CACCC box

Contributo in Atti di convegno

Differential Modulation of the ß-Like Globin Genes by KLFs Isolated with a g-Globin CACCC Bait.

Contributo in Atti di convegno

Direct Cost Analysis About The Three Chelators For The Treatment Of Thalassemia Patients With Chronic Iron Overload: An Italian Perspective From The MIOT Network

Abstract

Distinguishable live erythroid and myeloid cells in beta-globin ECFP x lysozyme EGFP mice

Articolo

ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia.

Articolo

EUROPEAN (DELTA-BETA)(O) THALASSEMIA - MOLECULAR CHARACTERIZATION OF A NOVEL 9.1-KB DELETION RESULTING IN HIGH-LEVELS OF FETAL HEMOGLOBIN IN THE ADULT

Articolo

Endogenous NGF regulates CGRP expression in human monocytes, and affects HLA-DR and CD86 expression and IL-10 production.

Articolo

Enhanced splenomegaly and severe liver inflammation in haptoglobin/hemopexin double-null mice after acute hemolysis

Articolo

Evidence that Amylogenic light chains undergo antigen-driven selection.

Articolo

Expression gradient in sheep alpha alpha and alpha alpha alpha globin gene haplotypes: mRNA levels

Articolo

Expression of the RET receptor tyrosine kinase and GDNF-Ra in normal and leukemic human hematopoietic cells and stromal cells of the bone marrow mic

Articolo

FLVCRb: a Mitochondrial FLVCR Isoform Important for Erythropoiesis

Abstract

Full-haplotype mismatched hematopoietic stem cell transplantation in patients with high risk hematological malignancies.

Abstract

G6PD is indispensable for erythropoiesis after the embryonic-adult hemoglobin switch

Articolo

Gender influences the birth order effect in HLA-identical Stem Cell Transplantation.

Articolo

Genetic Polymorphism of the Complement Receptor-1 (CR1) Gene Correlates with the Clinical Response to Eculizumab of Patients with Paroxysmal Nocturnal Hemoglobinuria (PNH)

Poster

Genetic and pharmacologic inactivation of cannabinoid CB1 receptor inhibits angiogenesis.

Articolo

HPFH From Klf1 Haploinsufficiency Combined to Transcriptional Heterozygous ?-Thalassemia

Abstract

Haptoglobin modifies the hemochromatosis phenotype in mice

Articolo

Heart T2*for Prediction of Cardiac Complications in Well-Treated TM Patients

Abstract

Hematopoietic stem cell function in b-thalassemia is impaired and is rescued by targeting the bone marrow niche

Articolo

Hemoglobin Neapolis, beta 126(H4)Val>Gly: a novel beta-chain variant associated with a mild beta-thalassemia phenotype and displaying anomalous stability features.

Articolo

High-definition mapping of retroviral integration sites identifies active regulatory elements in human multipotent hematopoietic progenitors

Articolo

High-level expression of hemoglobin A in human thalassemic erythroid progenitor cells following lentiviral vector delivery of an antisense snRNA

Articolo

Homozygosity for non-deletion delta-beta0 thalassemia resulting in a silent clinical phenotype

Articolo

Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature.

Articolo

Human CD34+ cells expressing membrane-bound tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) exert a potent anti-lymphoma effects by targeting tumor vasculature.

Abstract

Human herpesvirus 7 induces CD4(+) T-cell death by two distinct mechanisms: Necrotic lysis in productively infected cells and apoptosis in uninfected or nonproductively infected cells

Articolo

Human herpesvirus 8 acute infection of endothelial cells induces monocyte chemoattractant protein 1-dependent capillary-like structure formation: role of the IKK/NF-kappaB pathway

Articolo

Human immunodeficiency virus type 1 Nef activates STAT1 in human monocytes/macrophages through the release of soluble factors.

Articolo

Hypothyroidis and Cardiac Complications In Thalassemia Major Patients

Abstract

INTRACELLULAR HEME COORDINATELY MODULATES GLOBIN CHAIN SYNTHESIS, TRANSFERRIN RECEPTOR NUMBER, AND FERRITIN CONTENT IN DIFFERENTIATING FRIEND-ERYTHROLEUKEMIA CELLS

Articolo

Imatinib and pegylated human recombinant interferon-alpha2b in early chronic-phase chronic myeloid leukemia.

Articolo

Immune dysregulation in patients with RAG deficiency and other forms of combined immune deficiency

Articolo

Impact of allogeneic stem cell transplantation on survival of patients less than 65 years of age with primary myelofibrosis

Articolo

Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity

Articolo

In utero transplantation of adult bone marrow decreases perinatal lethality and rescues the bone phenotype in the knockin murine model for classical, dominant osteogenesis imperfecta.

Articolo

In vitro expression of the -87 ?-globin thalassemic mutations [5]

Articolo

In vitro expression of the -87 beta thalassemic mutation

Articolo

In vivo activation of the human delta globin gene promoter

Abstract

In vivo expression of human glucose 6-phosphate deydrogenase (hG6PD) after retroviral-mediated transfer into murine and human hematopoietic stem cells (HSC).

Abstract

In vivo targeting and growth inhibition of the A20 murine B-cell lymphoma by an idiotype-specific peptide binder

Articolo

Increased and pathologic emperipolesis of neutrophils within megakaryocytes associated with marrow fibrosis in GATA-1(low) mice,

Articolo

Induction of caspase-dependent programmewd cell death in B-cell chronic lymphocytic leukemia by anti-CD22 immunotoxins.

Articolo

Induction of gamma/delta T lymphocyte effector functions by bisphosphonate zoledronic acid in cancer patients in vivo.

Articolo

Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin

Articolo

Infant ALL patients carrying t(4;11) have a different genotypic profile than older ALL children

Abstract

Involvement of nitric oxide in farnesyltransferase inhibitor-mediated apoptosis in chronic myeloid leukemia cells.

Articolo

Involvement of the urokinase-type plasminogen activator receptor in hematopoietic stem cell mobilization

Articolo

JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subclone

Articolo

KLF1gene mutations cause borderline HbA2

Articolo

Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages

Articolo

Kit regulatory elements required for expression in developing hematopoietic and germ cell lineages

Articolo

LENTIVIRAL VECTORS EFFECTIVELY TRANSFER AND EXPRESS HUMAN GLUCOSE 6-PHOSPHATE DEHYDROGENASE (G6PD) IN PRIMITIVE HUMAN HEMATOPOIETIC CELLS (HSC) ENGRAFTING NOD/SCID MICE.

Poster

Lack of iNKT cells in patients with combined immune deficiency due to hypomorphic RAG mutations.

Articolo

Lack of progressive hepatic fibrosos during long-term therapy with deferiprone in subjects with transfusion-dependent-thalassemia

Articolo

Lineage- and stage-specific expression of runt box polypeptides in primitive and definitive hematopoiesis

Articolo

Long-lasting CCR5 internalization by antibodies in a subset of long-term nonprogressors: a possible protective effect against disease progression

Articolo

Long-term outcome and lineage-specific chimerism in 194 Wiskott-Aldrich Syndrome patients treated by hematopoietic cell transplantation between 1980-2009: an international collaborative study.

Articolo

Low Risk IPSS/DIPSS Primary Myelofibrosis: Identification of Patients with Higher Risk of Progression

Abstract

Magnetic Resonance T2* Technique for Segmental and Global Quantification of Myocardial Iron : Multi-Centre Validation in the MIOT (Myocardial Iron Overload in Thalassemia) network

Abstract

Measurement of spleen volume by ultrasound scanning in patients with thrombocytosis: a prospective study

Articolo

MicroRNAs modulate the angiogenic properties of HUVECs

Articolo

Missense mutation and defective function of ATM in a childhood acute leukemia patient with MLL gene rearrangement

Articolo

Missense mutations in the Fas gene resulting in autoimmune lymphoproliferative syndrome: A molecular and immunological analysis

Articolo

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150

Articolo

Modulation of microRNA expression in human T-cell development: targeting of NOTCH3 by miR-150

Articolo

Molecualar Basis of ?delta ß-thalassemia with normal HbF.

Articolo

Molecular response to imatinib in late chronic-phase chronic myeloid leukemia.

Articolo

Molecular-basis of chronic hemolytic nonspherocytic anemia in southern italy - 5 cases of interaction of hb variants and beta-thalassemia

Poster

Monoclonal antibody F1 binds to the Kringle domain of Factor XII and induces enhanced susceptibility for cleavage by kallikrein

Articolo

Multiple G6PD mutations are associated with a clinical and biochemical phenotype similar to that of G6PD Mediterranean.

Articolo

Multislice Multiecho T2* Cardiovascular Magnetic Resonance Detects Heterogeneous Myocardial Iron Distribution in Thalassemia Patients

Abstract

Myeloid lncRNA LOUP mediates opposing regulatory effects of RUNX1 and RUNX1-ETO in t(8;21) AML

Articolo

NFI-A directs the fate of hematopoietic progenitors to the erythroid or granulocytic lineage and controls -globin and G-CSF receptor expression

Articolo

Novel Chimeric Transcripts Involving PAX5 in B-Cell Precursor ALL

Abstract

Oncogene-induced maladaptive activation of trained immunity in the pathogenesis and treatment of Erdheim-Chester disease

Articolo

PKCepsilon controls protection against TRAIL in erythroid progenitors,

Articolo

PRIMARY STRUCTURE OF HUMAN ERYTHROCYTE NICOTINAMIDE ADENINE-DINUCLEOTIDE PHOSPHATE (NADP[H])-BINDING PROTEIN FX - IDENTIFICATION WITH THE MOUSE TUM(-) TRANSPLANTATION ANTIGEN P35B

Articolo

Phenotypic and functional analysis of Fas (CD95) expression in primary central nervous system lymphoma of patients with acquired immunodeficiency syndrome

Articolo

Platelet diameters in inherited thrombocytopenias: Analysis of 376 patients with all known disorders

Articolo

Position-independent expression of human glucose-6-phosphate dehydrogenase (HG6PD) driven by its own promoter after retroviral-mediated gene transfer and integration.

Abstract

Preclinical Rationale for the Use of the Multikinase Inhibitor Sorafenib in the Treatment of Human Lymphomas.

Poster

Prognostic significance of terminal transferase and adenosine deaminase in acute and chronic myeloid leukemia

Articolo

Recurrent mutations and three novel rearrangements in the factor VIII gene of hemophilia

Articolo

Redox regulation of T-cell turnover by the p13 protein of human T-cell leukemia virus type 1: distinct effects in primary versus transformed cells.

Articolo

Regulation of the Human Alpha-Globin Genes by GKLF

Contributo in Atti di convegno

Reliable typing of systemic amyloidoses through proteomic analysis of subcutaneous adipose tissue.

Articolo

Results and Cost Effectiveness of "on-Demand" Plerixafor Added to Chemotherapy and Granulocyte Colony-Stimulating Factor for Peripheral Blood Stem Cell Mobilization in Multiple Myeloma

Articolo

Retroviral mediated expression of the human glucose 6 phosphate deydrogenase (HG6PD) gene rescue G6PD deficient phenotype of G6PD-null embryonic stem (ES) cells.

Abstract

Retroviral mediated gene transfer of human glucose-6-phosphate dehydrogenase a (hG6PD A) into human hematopoietic progenitor cells.

Abstract

Retroviral mediated transfer and expression of the human glucose 6-phosphate dehydrogenase (G6PD) gene in mouse bone marrow cells

Abstract

Serum Hepcidin Levels Correlate with Phenotypes of the Metabolic Syndrome At Population Level

Abstract

Stable in vivo expression of glucose-6-phosphate dehydrogenase (G6PD) and rescue of G6PD deficiency in stem cells by gene transfer

Articolo

Structural Variations Identified By Whole Transcriptome Sequencing (RNA-Seq) in Childhood ALL with Different Response to Therapy

Abstract

Structural and functional analysis of two developmental mutants with discrete phenotypes using chromosome mediated gene transfer.

Articolo

T-cell defects in patients with ARPC1B germline mutations account for combined immunodeficiency

Articolo

THALASSEMIA-INTERMEDIA CAUSED BY BETA+ -87-C-]G MUTATION NOT ASSOCIATED IN CIS WITH -158-G-GAMMA-C-]T

Abstract

TMPRSS6 rs855791 modulates hepcidin transcription in vitro and serum hepcidin levels in normal individuals

Articolo

Targeting mesenchymal stromal cells plasticity to reroute acute myeloid leukemia course: MSC and AML dual targeting to treat pediatric AML

Articolo

Targeting of GSK3 beta promotes imatinib-mediated apoptosis in quiescent CD34(+) chronic myeloid leukemia progenitors, preserving normal stem cells

Articolo

Thalassemia-intermedia caused by beta+ -87 C>G mutation not associated in cis with -158-G-gamma-C>T

Abstract

The GATA-1 knock-down mutation impairs mast cell differentiation.

Abstract

The Prognostic Role of Diabetes Mellitus for Cardiac Complications in a Large Cohort of Well Treated Thalassemia Major Patients

Abstract

The antileukemia effect of HLA-matched NK and NK-T cells in chronic myelogenous leukemia involves NKG2D-target-cell interactions

Articolo

The effect on survival of bone marrow and blood involvement in non-Hodgkin's lymphoma (NHL). A retrospective study of 962 cases.

Articolo

The human beta-globin locus introduced by YAC transfer exhibits a specific and reproducible pattern of developmental regulation in transgenic mice

Articolo

The metastasis-associated 67-kDa laminin receptor is involved in G-CSF-induced hematopoietic stem cell mobilization.

Articolo

The n-terminal 11 amino acids of human erythrocyte band 3 are critical for aldolase binding and protein phosphorylation: implications for band 3 function

Articolo

Thymosin alpha 1 activates dendritic cells for antifungal Th1 resistance through toll-like receptor signaling

Articolo

Thymosin alpha1 activates dendritic cell tryptophan catabolism and establishes a regulatory environment for balance of inflammation and tolerance.

Articolo

Translocation breakpoints are clustered on both chromosome 8 and chromosome 21 in the t(8;21) of acute myeloid leukemia

Articolo

Tumor Suppressors BTG1 and BTG2 Fulfill Both Unique and Overlapping Functions During Normal B Lymphocyte Development

Articolo

Tumor Suppressors Btg1 and Btg2 Regulate B Lineage Commitment through Modulation of Ebf1 Activity

Articolo

Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child

Articolo

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Poster

No Results Found

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