Crystal structure and conformational analysis of the cognition activator 5-ethoxy-3-hydroxy-1-(phenylsulphonyl)pyrrolidin-2-one

The preferred crystalline, solution and in vacuo arrangements of the title compound were investigated by means of single crystal X-ray diffraction, H-1 NMR spectroscopy and molecular mechanics calculations, respectively, and the findings were compared with those obtained for two similar compounds. The X-ray powder pattern diffraction was also collected.