Enantioselective addition of diethylzinc to benzaldehyde in the presence of sulfur-containing pyridine ligands

Diastereomerically pure hydroxy and thiol derivatives of (5S,7S)-5,7-methane-6,6-dimethyl-2-phenyl-5,6,7,8- tetrahydroquinoline were prepared and assessed in the enantioselective addition of diethylzinc to benzaldehyde: enantioselectivities up to 62% were obtained.