MicroRNA target and gene validation in viruses and bacteria.

Noncoding RNAs (ncRNAs) constitute an evolutionary conserved system involved in the regulation of biological functions at posttranscriptional level. The capability to rapidly adapt their metabolism is essential for the survival of organisms. NcRNAs are a valuable means used by cells to rapidly transfer and internalize an external signal. NcRNAs are capable not only to influence the translational phase but also to affect epigenetic processes. They have been identified in almost all kingdoms of life (from archaea to human and plants). In this chapter we outline the currently available resources that could be used for the screening of viral and bacterial ncRNAs.