Multitarget opioid ligands in pain relief: New players in an old game

MU-AGONIST/DELTA-ANTAGONIST; PROTEIN-COUPLED RECEPTORS; DESIGNED MULTIPLE LIGAND; DMT-TIC PHARMACOPHORE; BIVALENT LIGANDS; IN-VITRO; BIOLOGICAL EVALUATION; BINDING-AFFINITY; DELTA-ANTAGONIST; DPI-3290 (+)-3-((ALPHA-R)-ALPHA-((2S; 5R)-4-ALLYL-2; 5-DIMETHYL-1-PIPERAZINYL)-3-HY DROXYBEN