ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex

Highlights o ZBTB2 co-associate with the NuRD complex. o The multiple ZBTB2 functions can be explained because of its interplay with NuRD. o ZBTB2 can be a bridge between NuRD and DNA-sequence specific transcription factors. o ZBTB2 interactome by mass-spectrometry reveals the presence of many chromatin remodeling complex subunits. o ZBTB2 interacts with ZNF639, a sequence-specific DNA-binding zinc-finger protein.