The Interplay of Monolayer Structure and Serum Protein Interactions on the Cellular Uptake of Gold Nanoparticles

Academic Article
Publication Date:
2012
abstract:
In this work we investigated how serum protein adsorption on NP surfaces infl uences the cellular uptake of NPs. We fi nd that surface hydrophobicity is a critical factor for controlling serum albumin binding, which in turn decreases the cellular uptake of AuNPs.
Iris type:
01.01 Articolo in rivista
Keywords:
gold nanoparticles; cellular uptake; hydrophobicity; protein absorption; structure-protein interactions
List of contributors:
Authors of the University:
Handle:
https://iris.cnr.it/handle/20.500.14243/394017
Published in:
SMALL (WEINH., PRINT)
Journal