2JJP Structure of cytochrome P450 EryK in complex with inhibitor ketoconazole (KC)

Altro Prodotto di Ricerca
Data di Pubblicazione:
2009
Abstract:
EryK is a bacterial cytochrome P450 that catalyzes the last hydroxylation occurring during the biosynthetic pathway of erythromycin A in Streptomyces erythraeus. We report the crystal structures of EryK in complex with two widely used azole inhibitors: ketoconazole and clotrimazole.
Tipologia CRIS:
05.10 Dataset
Keywords:
OXIDOREDUCTASE; Saccharopolyspora erythraea; Erythromycin A
Elenco autori:
Autori di Ateneo:
Link alla scheda completa:
https://iris.cnr.it/handle/20.500.14243/305550