Publication Date:
2016
abstract:
The photodynamic activity occurring through the lysosome photo-damage is effective in terms of triggered synergic
effectswhich can avoid chemo-resistance pathways. The potential photodynamic activity of twofluorescent
lysosome-specific probes was studied providing their interaction with human serum albumin, demonstrating
their in vitro generation of singlet oxygen and investigating the resulted photo-toxic effect in human cancer cells.
Iris type:
01.01 Articolo in rivista
Keywords:
Thiophene dyes Lysosomes Photosensitizers Singlet oxygen Reactive oxygen species Human serum albumin
List of contributors:
Capodilupo, AGOSTINA LINA
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