Protein translocation through graphene nanopores

Nanopore sensing is an emerging technique to analyze macromolecules at single-molecule level. In nanopore sensing a voltage is applied between the two sides of the membrane and, consequently, a ionic current flows through the nanopore [1]. When a molecule translocates across the nanopore, a change in the current is measured. The current signal, in principle, allows to obtain information on the translocating molecule. A number of different nanopores (both biological and solid state) have been employed for different applications, such as DNA sequencing, protein-DNA interaction and polypeptide folding [2]. ... ...