Modulation of methotrexate efficacy by green tea polyphenols in rat adjuvant arthritis
Academic Article
Publication Date:
2020
abstract:
Background: Green tea catechins are widely employed as dietary supplements to restore the oxidative state in adjuvant-induced arthritic rats, a model for human rheumatoid arthritis. Methotrexate is the first line anti rheumatic drug. The present study aimed to investigate if a decaffeinated extract (GreenSelect (R), GS) of tea polyphenols can ameliorate methotrexate treatment in rat adjuvant arthritis.
Iris type:
01.01 Articolo in rivista
Keywords:
Arthritis; Green tea polyphenols; Methotrexate; Inflammation; Antioxidants
List of contributors:
Gardi, Concetta; Russo, GIAN LUIGI; Tedesco, Idolo
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