From Gene Ontology to Cell Ontology: interoperability among biological knowledge bases

We detected some new representation anomalies in Gene Ontology beside the ones already reported in literature. We constructed a new ontology, named Cell Ontology, that not exhibit these representation anomalies and introduces new concepts to represent molecular biology knowledge. We also built an user interface that allow to share (provide and harvest) metadatarecords (interoperability) among different biological ontologies (in the specific case between Gene Ontology and Cell Ontology). The software architecture of this interface allows interoperability between data schemata of different ontologies and was built using some libraries of XSB Prolog and Flora2: Interprolog and Java2Flora.