Alkynyl-2-deoxy-D-riboses, a cornucopia for the generation of families of C-nucleosides

This study focuses on the preparation of some 1-alkynyl-2-deoxy-D-riboses and their application to the generation of C-nucleosides analogues Examples are provided in which the alkyne functionality took part in allkylation or cycloaddition reactions A discussion of the protecting group used is provided (C) 2010 Elsevier Ltd All rights reserved