ANALYSIS OF RETINAL CAPILLARIES IN PATIENTS WITH TYPE 1 DIABETES AND NONPROLIFERATIVE DIABETIC RETINOPATHY USING ADAPTIVE OPTICS IMAGING

Purpose: To illustrate a noninvasive method to analyze the retinal capillary lumen caliber in patients with Type 1 diabetes. Methods: Adaptive optics imaging of the retinal capillaries were acquired in two parafoveal regions of interest in eyes with nonproliferative diabetic retinopathy and unaffected controls. Measures of the retinal capillary lumen caliber were quantified using an algorithm written in Matlab by an independent observer in a masked manner. Comparison of the adaptive optics images with red-free and color wide fundus retinography images was also assessed.