Target-induced amplification in a dynamic library of macrocycles. A quantitative study

The perturbation caused by a silver template on the composition of a DCL of cyclophane formaldehyde acetals was investigated as a function of monomer concentration ranging from dilute solutions to values approaching the critical monomer concentration. The target-induced amplification of the dimeric macrocycle was quantitatively analyzed in terms of effective molarity of the macrocycle in the absence and presence of the target.