Continuity diagram analysis at open loop and closed loop to improve the operability of a bioreactor

The paper analyzes the dynamics of a simple biochemical reactor model with a substrate inhibition kinetics under open as well as closed loop configuration and discusses the system continuity diagram in both cases. The controller chosen for closed loop system is a traditional proportional integral controller. Attention is focused on the effects that open loop and closed loop models have on dynamics of the same system and how the nature of the continuity diagram changes when moving just from an open system to a controlled system. The closed loop configuration proves to give the advantage of greatly improving the operability of the bioreactor around the point that is optimal with reference to substrate conversion and biomass production.