Confocal dual-pulse electrohydraulic shock wave therapy for advanced atherosclerosis regression accompaniedby atorvastatin-loaded microbubbles administration

Atherosclerosis is the leading cause of cardiovascular disease. The management of atherosclerosis reduces the risk of myocardial infarction and its related deaths. In this study, we developed an experimental confocal dual-pulse (20 Kv, 0.1 Hz and 8 Kv, 5 Hz) electrohydraulic shock wave generator, and investigated its effectiveness on advanced atherosclerotic plaque regression.