Nanotheranostic tools engineered with Cyclodextrins and Photosensitisers assemblies

Cyclodextrin are suitable host molecules especially used for drug entrapment and delivery. Our goals is to design and characterize biodegradable amphiphilic cyclodextrin able to host, deliver and especially target a drug in the sites of action. These carriers, have a size compatible with i.v. injection and posses high potential to optimize drug distribution in the body, and selectively deliver anticancer [1,2], photosensitiser for Photodynamic Therapy of Tumors (PDT) [3], metal nanoparticles [4], DNA for gene therapy [5 ] or combined dose of therapeutics [6] and /or diagnostic probe for theranostic [7].This multifunctional nanoconstructs can be engineered with stimuli-responsive probes i.e. pH, magnetic field, light , redox potential [8], or combined with nanoplatform based on graphene and/or MWCNT [9] to give dispositives for investigating cell behavior. Recent investigations and results will be here discussed.