Genomic analysis of serotonin receptors in learning and memory

The completion of the Human Genome Project and a variety of new technologies, such as DNA microarray technology, are revolutionizing the way molecular mechanisms underlying learning and memory can be explored. This review highlights the use of a genomic approach to dissect and analyze the complex dynamic interactions involved in gene regulation during learning and memory and illustrates the changes of serotonin receptor subtypes observed in different time domains and behavioral paradigms. (C) 2007 Elsevier B.V. All rights reserved.