Role of Lipid Peroxidation and PPAR-delta in Amplifying Glucose-Stimulated Insulin Secretion
Articolo
Data di Pubblicazione:
2011
Abstract:
OBJECTIVE-Previous studies show that polyunsaturated fatty acids (PUFAs) increase the insulin secretory capacity of pancreatic beta-cells. We aimed at identifying PUFA-derived mediators and their cellular targets that are involved in the amplification of insulin release from beta-cells preexposed to high glucose levels.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
diabetes; lipidomics; membrane remodeling
Elenco autori:
Ferreri, Carla; Chatgilialoglu, Chryssostomos
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