Data di Pubblicazione:
2022
Abstract:
Inositols (Ins) are natural compounds largely widespread in plants and animals. Biosinthetically they derive from sugars, possessing a molecular structure very similar to the simple
sugars, and this aspect concurs to define them as primary metabolites, even though it is much more
correct to place them at the boundary between primary and secondary metabolites. This dichotomy
is well represented by the fact that as primary metabolites they are essential cellular components in
the form of phospholipid derivatives, while as secondary metabolites they are involved in a plethora
of signaling pathways playing an important role in the surviving of living organisms. myo-Inositol is
the most important and widespread compound of this family, it derives directly from D-glucose, and
all known inositols, including stereoisomers and derivatives, are the results of metabolic processes
on this unique molecule. In this review, we report the new insights of these compounds and their
derivatives concerning their occurrence in Nature with a particular emphasis on the plant of the
Mediterranean area, as well as the new developments about their biological effectiveness
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
inositols; natural occurrence; biological role; bioactivity
Elenco autori:
Napoli, EDOARDO MARCO; Siracusa, Laura; Ruberto, Giuseppe
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