Proceedings of the 12th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics

CIBB (Computational Intelligence methods for Bioinformatics and Biostatistics) is a meeting with more than 10-year of history. Its main goal is to provide a forum open to researchers from different disciplines to present problems concerning computational techniques in bioinformatics, systems biology and medical informatics, to discuss cutting edge methodologies and accelerate life science discoveries. Following this tradition and roots, this year's meeting will bring together researchers from the international scientific community interested in this field to discuss the advancements and the future perspectives in bioinformatics and biostatistics. Applied biologists are also invited to participate in order to propose novel challenges aimed to have high impact for molecular biology and translational medicine. The location is the CNR Research Area Napoli 1, in Naples Italy. CNR Research Area Napoli 1 is the Biomedical and Biotechnological Centre of the National Research Council in Naples. Technical areas addressed by CIBB 2015 include, but are not limited to: High dimensional statistical analysis of omic data; Next generation sequencing bioinformatics; Multi-omic data integration; Methods for supervised and unsupervised learning; Prediction of protein structures; Methods for comparative genomics; Algorithms for molecular evolution and phylogenetic analysis; Mathematical modelling and simulation of biological systems; Systems and synthetic biology; Bio-molecular databases and data mining; Bio-medical text mining and imaging; Statistical methods for the analysis of clinical data; Methods for the visualization of high dimensional complex omic data; Software tools for bioinformatics. The scientific program includes, besides some plenary talks, contributed papers that will be presented as regular and short oral talks in dedicated sessions. Accepted papers will be published in the conference proceedings. A selection of papers presented at CIBB 2015 will be published in extended form in a post conference volume of LNBI printed by Springer. Moreover, we are planning to publish the best papers in extended form in a special issue of BMC Bioinformatics. Five special sessions are organized at CIBB 2015: o The EDGE, enhanced definition of genomic entities for systems biomedicine in oncology, o New knowledge from old data: power of data analysis and integration methods, o Regularization methods for genomic data analysis, o Large-Scale and HPC data analysis in bioinformatics: intelligent methods for computational, systems and synthetic biology, o Multi Omic metabolic models and statistical Bioinformatics of adaptations and biological associations. More information about CIBB2015 can be found at the CIBB website http://bioinfo.na.iac.cnr.it/cibb2015/.