Neutral and charged copper(I) complexes on hydrophilic gold nanoparticles and nanorods: loading and structural studies for biomedical applications

In this framework AuNPs and AuNRs were synthetized with the aim to obtain strongly hydrophilic materials, suitable for drug delivery.[4-6] AuNPs were used as drug delivery systems for two different copper(I)-based anti-tumor complexes namely [Cu(PTA)4]+[BF4]- (A; PTA = 1,3,5-triaza-7-phosphadamantane) and [HB(pz)3Cu(PCN)] (B; HB(pz)3 = tris(pyrazolyl)borate, PCN = tris(cyanoethyl)phosphane).