Calcium signaling in the cochlea - Molecular mechanisms and physiopathological implications
Academic Article
Publication Date:
2012
abstract:
Calcium ions (Ca2+) regulate numerous and diverse aspects of cochlear and vestibular physiology. This review focuses on the Ca2+ control of mechanotransduction and synaptic transmission in sensory hair cells, as well as on Ca2+ signalling in non-sensory cells of the developing cochlea.
Iris type:
01.01 Articolo in rivista
Keywords:
Hearing; Inner ear; Transducer adaptation; Ca2+ channels; Cadherin 23; Protocadherin 15; Plasma-membrane Ca2+-ATPase; Prestin; Intracellular stores; Calcium release; Mitochondria; Ribbon synapse; Adenosine-5 '-triphosphate; Inositol 1; 4; 5-trisphosphate; Connexin 26; Connexin 30; Deafness; Mouse models
List of contributors:
Mammano, Fabio
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