Induction of cytochrome P450 1A by beta-naphtoflavon within the pig liver and central nervous system

The cytochromes P450 play a key role in the metabolism of both endogenous compounds such as steroids, cytokines, fatty acids, D vitamins, and xenobiotics including drugs and environmental contaminants. The purpose of this work was to investigate the expression and the induction of CYP1A within brain regions and the liver of pigs after treatment with beta-naphtoflavon.