Data di Pubblicazione:
2020
Abstract:
Herkenne et al. report that the mitochondria-shaping protein OPA1 is an essential component of both developmental and tumor angiogenesis. They discover a first-in-class small molecule that is specific to OPA1 and can pharmacologically target endothelial OPA1 to curtail tumor growth.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
Angiogenesis; cancer; fusion-fission; lymphangio; genesis; metastasis; mitochondria; mouseNF?B; Opa1; tumor; zebrafish
Elenco autori:
DI BENEDETTO, Giulietta
Link alla scheda completa:
Pubblicato in: