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Travelling wave solutions of a parabolic-hyperbolic system for contact inhibition of cell-growth

Articolo
Data di Pubblicazione:
2015
Abstract:
We consider a cell growth model involving a nonlinear system of partial differential equations which describes the growth of two types of cell populations with contact inhibition. Numerical experiments show that there is a parameter regime where, for a large class of initial data, the large time behaviour of the solutions is described by a segregated travelling wave solution with positive wave speed c. Here, the word segregated expresses the fact that the different types of cells are spatially segregated, and that the single densities are discontinuous at the moving interface which separates the two populations. In this paper, we show that, for each wave speed c > c, there exists an overlapping travelling wave solution, whose profile is continuous and no longer segregated. We also show that, for a large class of initial functions, the overlapping travelling wave solutions cannot represent the large time profile of the solutions of the system of partial differential equations. The structure of the travelling wave solutions strongly resembles that of the scalar Fisher-KPP equation, for which the special role played by the travelling wave solution with minimal speed has been extensively studied.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
a parabolic-hyperbolic system; contact inhibition of cells; Fisher-KPP equation; travelling wave solutions; tumour growth
Elenco autori:
Bertsch, Michiel
Link alla scheda completa:
https://iris.cnr.it/handle/20.500.14243/340351
Pubblicato in:
EUROPEAN JOURNAL OF APPLIED MATHEMATICS (PRINT)
Journal
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