3 'UTR SNPs and Haplotypes in the GATA4 Gene Contribute to the Genetic Risk of Congenital Heart Disease
Articolo
Data di Pubblicazione:
2016
Abstract:
Introduction and objectives: Single-nucleotide polymorphisms within a microRNA binding site can have different effects on gene expression, influencing the risk of disease. This study aimed to evaluate the association between single-nucleotide polymorphisms and haplotypes in the 3' UTR of the GATA4 gene and congenital heart disease risk.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
Haplotype; Single nucleotide polymorphisms; 3 ' UTR; GATA4; Congenital heart disease
Elenco autori:
Sabina, Saverio; Foffa, Ilenia; Vecoli, Cecilia; Andreassi, Mariagrazia; Pulignani, Silvia; AIT ALI', Lamia
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