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An Artificial Disc: Medical and Biomechanical Analysis

Articolo
Data di Pubblicazione:
2008
Abstract:
Degeneration of intervertebral discs is the most common cause of back pain. The first phase of this degenerative process involves the nucleus pulposus. A rapid recovery of this structure can prevent further degradation of the annulus fibrosus. Guar Gum is an hydrophilic polysaccharide extracted from the seed endosperm of a plant. Through a cross-linking procedure a Guar hydrogel was synthesized. The Guar hydrogel could be injected by a syringe and it is a good candidate as a nucleus pulposus substitute. For the preparation of the artificial fibrosus annulus, commercially available polymer materials are tuned to achieve suitable mechanical properties. To achieve this peculiar behaviour, the main strategy investigated is the dispersion of hollow polymer micro spheres in a thermoplastic polymer matrix. Processing conditions and particle content are finely tuned to get the target mechanical behaviour.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
annulus fibrosus; guar gum; hydrogel; intervertebral disc degeneration; nucleus pulposus
Elenco autori:
Ciardelli, Francesco; Signori, Francesca; Bronco, Simona
Autori di Ateneo:
BRONCO SIMONA
Link alla scheda completa:
https://iris.cnr.it/handle/20.500.14243/39084
Pubblicato in:
MACROMOLECULAR SYMPOSIA
Journal
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