Synthesis of Pterostilbene through supported-catalyst promoted Mizoroki-Heck reaction, and its transposition in continuous flow reactor

Pterostilbene, an important polyphenolic compound with interesting biological activities, has been efficiently synthesized through a Mizoroki-Heck reaction catalyzed by commercially available Pd catalysts immobilized onto heterogeneous supports. The synthesis has been transposed in a continuous flow reactor, following two different retrosynthetic approaches.