An optical sensor for pH supported onto tentagel resin beads

Covalent functionalization with a reactive azo-dye of tentagel resin beads bearing hydroxyl linkers led to a micro-sized optical sensor for pH detection. A PDMS/glass microfluidic cell has been constructed using replica molding combined with a fast prototyping procedure based on commercially available thiolene-based photocurable adhesives and used for studying the acid-base and time-response properties of the bead sensor under flow conditions. (C) 2007 Elsevier B.V All rights reserved.