Pseudo-Domino Palladium-Catalyzed Allylic Alkylation/Mizoroki-Heck Coupling Reaction: A Key sequence toward (±)-Podophyllotoxin

Academic Article
Publication Date:
2008
abstract:
A formal synthesis of podophyllotoxin was carried out in nine steps. The key pseudo-domino step was accomplished through the succession of an intermolecular palladium-catalyzed allylic alkylation and an intramolecular Mizoroki-Heck coupling reaction.
Iris type:
01.01 Articolo in rivista
Keywords:
Podoph; Catalysis; Domino; Palladium; Ring-closure
List of contributors:
Authors of the University:
Handle:
https://iris.cnr.it/handle/20.500.14243/33864
Published in:
TETRAHEDRON LETTERS
Journal