Pseudo-Domino Palladium-Catalyzed Allylic Alkylation/Mizoroki-Heck Coupling Reaction: A Key sequence toward (±)-Podophyllotoxin

Articolo

Data di Pubblicazione:

2008

Abstract:

A formal synthesis of podophyllotoxin was carried out in nine steps. The key pseudo-domino step was accomplished through the succession of an intermolecular palladium-catalyzed allylic alkylation and an intramolecular Mizoroki-Heck coupling reaction.

Tipologia CRIS:

01.01 Articolo in rivista

Keywords:

Podoph; Catalysis; Domino; Palladium; Ring-closure

Elenco autori: