Enanthioselective synthesis of protected D-serine from tetrahydrooxazin-4-one via hetero Diels-Alder reaction

Academic Article
Publication Date:
2002
abstract:
Hetero Diels-Alder reaction between 2-aza-3-trimethylsilyloxy-1,3-diene and aldehydes gives rise to tetrahydrooxazin-4-ones, useful intermediates in the synthesis of alpha-amino-beta-hydroxy acids. Herein we report the complete stereoselective synthesis of D-serine Cbz-methyl ester.
Iris type:
01.01 Articolo in rivista
Keywords:
ALPHA-AMINO-ACIDS; PRACTICAL STEREOSELECTIVE SYNTHESIS; BETA-HYDROXY; DIASTEREOSELECTIVE SYNTHESIS; ELECTROPHILIC AMINATION; ASYMMETRIC-SYNTHESIS; DERIVATIVES; THREONINES; RECEPTOR; ESTERS
List of contributors:
Authors of the University:
Handle:
https://iris.cnr.it/handle/20.500.14243/32147
Published in:
TETRAHEDRON. ASYMMETRY
Journal