Synthesis of Porphyrin C-Glycoconjugates

Two novel chiral porphyrin (5) and (7), with two and four alditolyl chains attached at the bridging methane carbons, have been synthesized via, respectively, coupling of the dipyrril unit (3) with p-fluorobenzaldehyde (4) and BF3-catalyzed condensation between pyrrole and 2,3-O-isopropylidene-D-glyceraldehyde (6).