Data di Pubblicazione:
2018
Abstract:
detectRUNS is a R package for the detection of runs of homozygosity (ROH/ROHom) and of heterozygosity (ROHet, a.k.a. "heterozygosity-rich regions") in diploid genomes. ROH/ROHom were first studied in humans (e.g. McQuillan et al. 2008) and rapidly found applications not only in human genetics abut also in animal genetics (e.g. Ferencakovic et al., 2011, in Bos taurus). More recently, the idea of looking also at "runs of heterozygosity" (ROHet or, more appropriately, "heterozygosity-rich regions") has been proposed (Wiliams et al. 2016).
Tipologia CRIS:
05.11 Software
Keywords:
runs of homozygosity; r package; runs of heterozygosity; inbreeding; recessive variants
Elenco autori:
Biscarini, Filippo
Link alla scheda completa: