YeastpRofile: A software to calculate profiles around TSS and TTS of yeast mRNAs

This software calculates the profile of a genomic variable around transcription start (TSS) and termination (TTS) sites of yeast mRNAs. Each profile is obtained by calculating the genome-wide Pearson correlation coefficient between the genomic variable values and the TSS (or TTS) counts at incremental shifting of genomic coordinates. The data relative to TSS and TTS counts used to compute the profiles were taken from the work of Pelechano et al. 2013 [1]. The TSS and TTS genomic positions are related to the release 64 of yeast coordinates. [1] V. Pelechano, W. Wei, L.M. Steinmetz, Extensive transcriptional heterogeneity revealed by isoform profiling, Nature, 497 (2013) 127-131.