Synthesis of luminescent 2,3-diphenylmaleimide-labelled peptide nucleic acid oligomers

Articolo
Data di Pubblicazione:
2018
Abstract:
A lys-GTAGATCACT-lys peptide nucleic acid (PNA) decamer labelled with the luminescent 2,3-diphenyl maleimido (DPM) group on the ?-position of the terminal lysine residue was prepared through an automated solid phase synthesis. Fluorescence emission of the DPM-labelled PNA thus obtained was found to be significant and promising for the potential application in DNA recognition.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
Peptide nucleic acids Solid phase synthesis Amino acids Maleimides Luminescence
Elenco autori:
Link alla scheda completa:
https://iris.cnr.it/handle/20.500.14243/373269
Pubblicato in:
TETRAHEDRON LETTERS
Journal