Merging of E2 and E1cb Reaction Mechanisms: A Combined Theoretical and Experimental Study
Academic Article
Publication Date:
2009
abstract:
By combining the results of kinetic measurements with DFT
calculations we provide a clear-cut evidence of the merging
between the E2 and E1cb reaction mechanisms for a large
series of leaving groups. Our results solve a long-debated
issue in chemical reactivity with profound implications both from a fundamental and biological point of view, thus paving
the way to further investigations with different substrates.
calculations we provide a clear-cut evidence of the merging
between the E2 and E1cb reaction mechanisms for a large
series of leaving groups. Our results solve a long-debated
issue in chemical reactivity with profound implications both from a fundamental and biological point of view, thus paving
the way to further investigations with different substrates.
Iris type:
01.01 Articolo in rivista
List of contributors:
Tarantelli, Francesco; Mosconi, Edoardo; DE ANGELIS, Filippo; Belpassi, Leonardo
Published in: