NEUROBIOLOGY OF DISEASE

Journal

Identifier:

E117221

ISSN:

0969-9961

Overview

Outputs (93)

1-(2',4'-dichlorophenyl)-6-methyl-N-cyclohexylamine-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide, a novel CB2 agonist, alleviates neuropathic pain through functional microglial changes in mice.

Academic Article

17beta-estradiol rescues spinal motoneurons from AMPA-induced toxicity: A role for glial cells.

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A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1+/- mice.

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A prolonged pharmacological blockade of type-5 metabotropic glutamate receptors protects cultured spinal cord motor neurons against excitotoxic death

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A voxel-based PET study of dopamine transporters in Parkinson's disease: relevance of age at onset.

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Activation of PPAR gamma receptors reduces levodopa-induced dyskinesias in 6-OHDA-lesioned rats

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Acute restraint stress impairs histamine type 2 receptor ability to increase the excitability of medium spiny neurons in the nucleus accumbens

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Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

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Adolescent exposure to THC in female rats disrupts developmental changes in the prefrontal cortex

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Altered calcium homeostasis in motor neurons following AMPA receptor but not voltage-dependent calcium channels' activation in a genetic model of amyotrophic lateral sclerosis

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Altered responses of dopamine D3 receptor null mice to excitotoxic or anxiogenic stimuli: Possible involvement of the endocannabinoid and endovanilloid systems

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An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells

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An endocannabinoid tone limits excitotoxicity in vitro and in a model of multiple sclerosis

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Apaf1 mediates apoptosis and mitochondrial damage induced by mutant human SOD1s typical of familial amyotrophic lateral sclerosis

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Brain-derived neurotrophic factor (BDNF) overexpression in the forebrain results in learning and memory impairments

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CXCR2 increases in ALS cortical neurons and its inhibition prevents motor neurons degeneration in vitro and improves neuromuscular function in SOD1G93A mice

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Cannabidiol inhibits microglia activation and mitigates neuronal damage induced by kainate in an in-vitro seizure model

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Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease

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Cell-specific expression of the epm1 (cystatin B) gene in developing rat cerebellum

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Cerebellar granule cells transplanted in vivo can follow physiological and unusual migratory routes to integrate into the recipient cortex.

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Cerebral collateral flow defines topography and evolution of molecular penumbra in experimental ischemic stroke

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Changes in the expression of extracellular regulated kinase (ERK 1/2) in the R6/2 mouse model of Huntington's disease after phosphodiesterase IV inhibition

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Corrigendum to AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons, [Neurobioly of Disease (2014) 62, 489-507] DOI: 10.1016/j.nbd.2013.10.018

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Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis

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Differential regulation of transcripts for dystrophin Isoforms, dystroglycan, and alpha3AChR subunit in mouse sympathetic ganglia following postganglionic nerve crush.

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Dopamine D2 receptor dysfunction is rescued by adenosine A2A receptor antagonism in a model of DYT1 dystonia

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Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-gamma agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease

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Dynamic changes in pro-and anti-inflammatory cytokines in microglia after PPAR-g agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease.

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Dysregulated autophagy as a new aspect of the molecular pathogenesis of Krabbe disease

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Dystrophin stabilizes ?3- but not ?7-containing nicotinic acetylcholine receptor subtypes at the postsynaptic apparatus in the mouse superior cervical ganglion

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Dystrophin stabilizes alpha 3- but not alpha 7-containing nicotinic acetylcholine receptor subtypes at the postsynaptic apparatus in the mouse superior cervical ganglion.

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Early environmental therapy rescues brain development in a mouse model of Down syndrome

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Evidence for chronic mitochondrial impairment in the cervical spinal cord of a murine model of motor neuron disease.

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Exocytosis regulates trafficking of GABA and glycine heterotransporters in spinal cord glutamatergic synapses: A mechanism for the excessive heterotransporter-induced release of glutamate in experimental amyotrophic lateral sclerosis

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Fluoxetine in adulthood normalizes GABA release and rescues hippocampal synaptic Plasticity and spatial memory in a mouse model of Down Syndrome

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Fragile X mental retardation protein (FMRP) and metabotropic glutamate receptor subtype 5 (mGlu5) control stress granule formation in astrocytes

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Functional and structural correlates of magnetic resonance patterns in a new in vitro model of cerebral ischemia by transient occlusion of the medial cerebral artery

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Gene co-expression networks shed light into diseases of brain iron accumulation

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Gene expression profiles in a transgenic animal model of fragile X syndrome

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Gene expression profiles in a transgenic animal model of fragile x syndrome

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Genes and pathways differentially expressed in the brains of Fxr2 knockout mice

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Impairment of PMP22 transgenig Schwann cells differentiatic in culture: implications for Charcot-Marie-Tooth type 1A disease

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In vitro drug treatments reduce the deleterious effects of aggregates containing polyAla expanded PHOX2B proteins.

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Increased transcription of transglutaminase 1 mediates neuronal death in in vitro models of neuronal stress and A beta 1-42-mediated toxicity

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Inflammatory cytokines increase mitochondrial damage in motoneuronal cells expressing mutant SOD1

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Integrative human and murine multi-omics: Highlighting shared biomarkers in the neuronal ceroid lipofuscinoses

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Interaction of Tau with Fe65 links tau to APP.

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Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders

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Interferon-gamma causes mood abnormalities by altering cannabinoid CB1 receptor function in the mouse striatum

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Intravitreal gene therapy restores the autophagy-lysosomal pathway and attenuates retinal degeneration in cathepsin D-deficient mice

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Lack of dystrophin functionally affects alpha 3 beta 2/beta 4-nicotinic acethylcholine receptors in sympathetic neurons of dystrophic mdx mice

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Lack of dystrophin functionally affects alpha3beta2/beta4-nicotinic acethylcholine receptors in sympathetic neurons of dystrophic mdx mice.

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Lamotrigine rescues neuronal alterations and prevents seizure-induced memory decline in an Alzheimer's disease mouse mode

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Lateral habenula dysfunctions in Tm4sf2(-/y) mice model for neurodevelopmental disorder

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Mechanism underlying unaltered cortical inhibitory synaptic transmission in contrast with enhanced excitatory transmission in Ca(V)2.1 knockin migraine mice

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Megalencephalic leukoencephalopathy with subcortical cysts protein-1 modulates endosomal pH and protein trafficking in astrocytes: Relevance to MLC disease pathogenesis

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Mislocalised FUS mutants stall spliceosomal snRNPs in the cytoplasm

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Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with amyotrophic lateral sclerosis is reversed by N-acetylcysteine.

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Mitochondrial dysfunction due to mutant copper/zinc superoxide dismutase associated with familial amyotrophic lateral sclerosis is reversed by n-acetyl-cysteine

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Mitochondrial iron and energetic dysfunction distinguish fibroblasts and induced neurons from pantothenate kinase-associated neurodegeneration patients

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Molecular classification of amyotrophic lateral sclerosis by unsupervised clustering of gene expression in motor cortex

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Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195.

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Motor neuron degeneration, severe myopathy and TDP-43 increase in a transgenic pig model of SOD1-linked familiar ALS

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N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion

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Neuroferritinopathy: From ferritin structure modification to pathogenetic mechanism

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Neutralization of a unique, negatively-charged residue in the voltage sensor of K V 7.2 subunits in a sporadic case of benign familial neonatal seizures.

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Oxidative brain damage in Mecp2-mutant murine models of Rett syndrome

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Pharmacological rescue of adult hippocampal neurogenesis in a mouse model of X-linked intellectual disability

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Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease

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Plastic and behavioral abnormalities in experimental Huntington's disease: a crucial role for cholinergic interneurons

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Protective activation of the endocannabinoid system during ischemia in dopamine neurons.

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Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor

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Reduced GABAB receptor subunit expression and paired-pulse depression in a genetic model of absence seizures

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Regionalized neurofilament accumulation and motoneuron degeneration are linked phenotypes in wobbler neuromuscular disease.

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Retrovirus mediated gene transfer and cross-correction of galactocerebrosidase in twitcher glial cells results in appropriate localization and phenotype correction

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Selective defects in channel permeability associated with Cx32 mutations causing X-linked Charcot-Marie-Tooth disease

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Selective nicotinic acetylcholine receptor subunit deficits identified in Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies by immunoprecipitation

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Structural insights into the multi-determinant aggregation of TDP-43 in motor neuron-like cells

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Substance P receptor activation induces downregulation of the AMPA receptor functionality in cortical neurons from a genetic model of Amyotrophic Lateral Sclerosis.

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Synaptic alterations as a neurodevelopmental trait of Duchenne muscular dystrophy

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T 1 AM-TAAR1 signalling protects against OGD-induced synaptic dysfunction in the entorhinal cortex

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TGF-beta 1 protects against Abeta-neurotoxicity via the phosphatidylinositol-3-kinase pathway

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TGF-ß1 protects against Aß-neurotoxicity via the phosphatidylinositol-3-kinase pathway.

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The endocannabinoid system is modulated in response to spinal cord injury in rats.

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The first reported generation of several induced pluripotent stem cell line from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity

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The metabotropic P2Y4 receptor participates in the commitment to differentiation and cell death of human neuroblastoma SH-SY5Y cells.

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Transcriptional dysregulation and impairment of PHOX2B auto-regulatory mechanism induced by polyalanine expansion mutations associated with congenital central hypoventilation syndrome

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Transient upregulation of translational efficiency in prodromal and early symptomatic Tg2576 mice contributes to Abeta pathology

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Ultra-micronized palmitoylethanolamide ...

Academic Article

Ultra-micronized palmitoylethanolamide rescues the cognitive decline-associated loss of neural plasticity in the neuropathic mouse entorhinal cortex-dentate gyrus pathway

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UsnRNP trafficking is regulated by stress granules and compromised by mutant ALS proteins.

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WDR79/TCAB1 plays a conserved role in the control of locomotion and ameliorates phenotypic defects in SMA models

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h channel-dependent deficit of theta oscillation resonance and phase shift in temporal lobe epilepsy

Academic Article

No Results Found

NEUROBIOLOGY OF DISEASE

Overview

Outputs (93)