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JOURNAL OF MEDICINAL CHEMISTRY (ONLINE)
Rivista
Codice:
E201391
ISSN:
1520-4804
Dati Generali
Dati Generali
Pubblicazioni (40)
Pulisci
Ordina Pubblicazioni:
ascendente
decrescente
1,4-Substituted Triazoles as Nonsteroidal Anti-Androgens for Prostate Cancer Treatment
Articolo
Allosteric Modulators of HSP90 and HSP70: Dynamics Meets Function through Structure-Based Drug Design
Articolo
CB2-Selective Cannabinoid Receptor Ligands: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of 1,8-Naphthyridin-2(1H)-one-3-carboxamides.
Articolo
Chiral Indolylarylsulfone Non-Nucleoside Reverse Transcriptase Inhibitors as New Potent and Broad Spectrum Anti-HIV-1 Agents
Articolo
DNA cloning, characterization and inhibition studies of an alpha-carbonic anhydrase from the pathogenic bacterium Vibrio cholerae.
Articolo
Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors
Articolo
Design, Synthesis, and Physicochemical and Pharmacological Profiling of 7-Hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide Derivatives with Antiosteoarthritic Activity In Vivo
Articolo
Design, synthesis, and biological evaluation of pyrazolo[3,4-d]pyrimidines active in vivo on the Bcr-Abl T315I mutant
Articolo
Design, synthesis, and biological evaluation of sirtinol analogues as class III histone/protein deacetylase (Sirtuin) inhibitors.
Articolo
Design, synthesis, and pharmacological characterization of indol-3-ylacetamides, indol-3-yloxoacetamides, and indol-3-ylcarboxamides: potent and selective CB2 cannabinoid receptor inverse agonists.
Articolo
Development and in Vitro Evaluation of a Microbicide Gel Formulation for a Novel Non-Nucleoside Reverse Transcriptase Inhibitor Belonging to the N-Dihydroalkyloxybenzyloxopyrimidines (N-DABOs) Family
Articolo
Development of potent carbonic anhydrase inhibitors incorporating both sulfonamide and sulfamide groups.
Articolo
Discovery of Novel Naphthylphenylketone and Naphthylphenylamine Derivatives as Cell Division Cycle 25B (CDC25B) Phosphatase Inhibitors: Design, Synthesis, Inhibition Mechanism and in Vitro Efficacy against Melanoma Cell Lines
Articolo
Discovery of glycine sulfonamides as dual inhibitors of sn-1-diacylglycerol lipase ? and ?/?-hydrolase domain 6
Articolo
Discovery of novel and selective SIRT6 inhibitors
Articolo
Discovery of the First Potent and Selective Inhibitors of Human dCTP Pyrophosphatase 1
Articolo
Exploring Translocator Protein (TSPO) Medicinal Chemistry: An Approach for Targeting Radionuclides and Boron Atoms to Mitochondria
Articolo
Hypoxia-targeting carbonic anhydrase IX inhibitors by a new series of nitroimidazole-sulfonamides/sulfamides/sulfamates
Articolo
Identification of the first PPARa/g able to bind to canonical and alternate sites of PPARg and to inhibit its Cdk-5-mediated phosphorylation
Articolo
Indole-2-carboxamides as allosteric modulators of the cannabinoid CB1 receptor.
Articolo
Insights into Current Tropomyosin Receptor Kinase (TRK) Inhibitors: Development and Clinical Application
Articolo
Insights into PPARgamma Phosphorylation and Its Inhibition Mechanism
Articolo
Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent alfa4beta2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the ?3?4 Subtype
Articolo
Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach +
Articolo
New nucleotide-competitive non-nucleoside inhibitors of terminal deoxynucleotidyl transferase: Discovery, characterization, and crystal structure in complex with the target
Articolo
Nitric Oxide Photo-Donor Hybrids of Ciprofloxacin and Norfloxacin: A Shift in Activity from Antimicrobial to Anticancer Agents
Articolo
RNA-binding and viral reverse transcriptase inhibitory activity of a novelcationic diamino acid-based peptide.
Articolo
Role of Ligands in the Uptake and Reduction of V(V) Complexes in Red Blood Cells
Articolo
Ruthenium-Arene Complexes of Curcumin: X-Ray and Density Functional Theory Structure, Synthesis, and Spectroscopic Characterization, in Vitro Antitumor Activity, and DNA Docking Studies of (p-Cymene)Ru(curcuminato)chloro
Articolo
Semisynthesis, Biological Activity, and Molecular Modeling Studies of C-Ring-Modified Camptothecins
Articolo
Side chain cyclization based on serine residues: Synthesis, structure, and activity of a novel cyclic analogue of the parathyroid hormone fragment 1-11
Articolo
Small Peptide inhibitors of acetyl-Peptide hydrolase having an uncommon mechanism of inhibition and a stable bent conformation.
Articolo
Synthesis and Characterization of Novel Mono- And Bis-Guanyl Hydrazones as Potent and Selective ASIC1 Inhibitors Able to Reduce Brain Ischemic Insult
Articolo
Synthesis and Pharmacological Characterization of 2-(Acylamino)thiophene Derivatives as Metabolically Stable, Orally Effective, Positive Allosteric Modulators of the GABAB Receptor
Articolo
Targeted Nanoparticles for the Delivery of Novel Bioactive Molecules to Pancreatic Cancer Cells
Articolo
The cis-4-amino-L-proline residue as a scaffold for the synthesis of cyclic and linear endomorphin-2 analogues
Articolo
Toward highly potent cancer agents by modulating the C-2 group of the arylthioindole class of tubulin polymerization inhibitors.
Articolo
Tricyclic pyrazoles. 3. Synthesis, biological evaluation, and molecular modeling of analogues of the cannabinoid antagonist 8-chloro-1-(2',4'-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide.
Articolo
Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the
Articolo
Unique Domain for a Unique Target: Selective Inhibitors of Host Cell DDX3X to Fight Emerging Viruses
Articolo
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