A novel 2,3-diphenyl-4H-pyrido[1,2-a]pyrimidin-4-one derivative inhibits endothelial cell dysfunction and smooth muscle cell proliferation/activation

Academic Article

Publication Date:

2014

abstract:

Hyper-proliferation and migration of vascular smooth muscle cells and endothelial cell dysfunction are central events in the development of neo-intimal lesions.

Iris type:

01.01 Articolo in rivista

Keywords:

2; 3-Diphenyl-4H-pyrido[1; 2-a]pyrimidin-4-ones; 2-(3; 4-Dimethoxyphenyl)-3-phenyl-4H-pyrido[1; 2-a]pyrimidin-4-one; Human aortic smooth muscle cells; Human umbilical vein endothelial cells; Cell proliferation; Cell dysfunction

List of contributors:

Basta, Giuseppina; DEL TURCO, Serena

Authors of the University:

BASTA GIUSEPPINA

DEL TURCO SERENA

Handle:

https://iris.cnr.it/handle/20.500.14243/253733

Published in:

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Journal