A new role for plant R2R3-MYB transcription factors in cell cycle regulation

MYB proteins are transcription factors present in all eukaryotes, sharing a common DNA-binding domain that consists of one to three imperfect helix-helix-turn-helix repeats of about 50 amino acids, called R1, R2, and R3 respectively 1. In animals and yeast these proteins represent a small gene family 1. Animal R1R2R3-MYB proteins have been described for their role in cell cycle regulation mainly at the G1/S, but also at the G2/M transition, as firstly demonstrated in Drosophila 2.