Data di Pubblicazione:
1990
Abstract:
Several cyclic oligodeoxynucleotides with different base composition and size have been prepared from 5?,3?-unprotected linear precursors, using a bifunctional phosphorylating reagent. The final deprotected ollgomers have been characterized by 1H- and 31P-NMR. The present procedure is particularly useful for millimolar scale syntheses.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
cyclic oligonucleotides; solution synthesis; phosphorylation; NMR; MS
Elenco autori:
Tondelli, Luisa; Capobianco, Massimo
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