Axonal Odorant Receptors Mediate Axon Targeting

Odorant receptors play a critical role in the sensory map formation. Zamparo et al. find that axonal odorant receptors respond to cues expressed in the olfactory bulb. Among these, PEBP1 acts as a putative ligand of axonal receptors, and its genetic ablation results in a disrupted sensory map in vivo.