Horizontal gaze palsy with progressive scoliosis: is scoliosis linked to ROBO3 mutations?

In our recent paper by Ungaro et al. we dealt briefly with the etiology of the progressive scoliosis in patients with Horizontal Gaze Palsy With Progressive Scoliosis (HGPPS). Therefore, in order to give a better explanation on the putative correlation between ROBO3 mutations and scoliosis in HGPPS, we reviewed 50 articles reported in literature related with HGPPS and scoliosis from 2004 to 2017.