Sys-bio gateway: A framework of bioinformatics database resources oriented to systems biology

In this paper we present SysBio-Gateway, a framework of standard solution for data integration in bioinformatics and Systems Biology. In the context of several research projects, we developed a set of databases and related web interfaces to cover many levels of the biological system complexity. Furthermore several analysis tools have been developed and integrated in the web resources in order to cope with problems of data integration and mining in a systems perspective. The SysBio-Gateway, freely accessible at the URL http://www.itb.cnr.it/sysbio-gateway, offers access to all the presented resources, which concerns different levels of organization of biological living systems, from genes to organs, passing through proteins, protein families, cellular processes, tissues, and pathologies.