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Modeling contact inhibition of growth: Traveling waves

Academic Article
Publication Date:
2013
abstract:
We consider a simplified 1-dimensional PDE-model describing the effect of contact inhibition in growth processes of normal and abnormal cells. Varying the value of a significant parameter, numerical tests suggest two different types of contact inhibition between the cell populations: the two populations move with constant velocity and exhibit spatial segregation, or they stop to move and regions of coexistence are formed. In order to understand the different mechanisms, we prove that there exists a segregated traveling wave solution for a unique wave speed, and we present numerical results on the ``stability" of the segregated waves. We conjecture the existence of a non-segregated standing wave for certain parameter values.
Iris type:
01.01 Articolo in rivista
List of contributors:
Bertsch, Michiel
Handle:
https://iris.cnr.it/handle/20.500.14243/247253
Published in:
NETWORKS AND HETEROGENEOUS MEDIA
Journal
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