Regional personalized electrodes to select transcranial electric stimulation target: a computational study of the electric field distribution

Recently, a procedure to personalize the electrode to stimulate specific cortical regions by transcranial electric stimulations (tES) has been proposed. Results of these studies documented that the cortical excitability was differently modulated depending on where the personalized electrode was positioned, thus refining previous evidences that it is possible to focus the effects of tES by properly shaping and positioning the electrodes to target a region of interest of the cerebral cortex. This study aims to assess, through computational modelling techniques, the distribution of the electric field (E) induced by tES via the regional personalized (RePE) and the non-personalized (ReNPE) electrode.